News Rover is a Usenet newsreader that features a built-in search engine for finding files in any Usenet newsgroup. Just enter keywords and News Rover will instantly find matching files in any newsgroup. News Rover includes a built-in RAR/PAR processor for handing RAR file posts. News Rover fully supports .nzb descriptor files. News Rover also has a JPEG picture gallery, iPod/Windows Media Player transfer option, password protection and file encryption for privacy.

Read more about it here: News Rover

NewsBin Pro is a Fast and Smart Usenet Robot that downloads and decodes binary file attachments to Usenet posts. NewsBin saves you time by using multiple connections to maximize your available bandwidth and by automatically combining multipart binary posts to create one file. NewsBin is a smart robot because it will detect duplicate files, allows filtering of files by newsgroup, and can be configured to automatically scan your newsgroups 24x7 for your favorite files.

http://www.newsbin.com/ 

Designed from the ground up for getting large files like MP3, RAR, and ZIP from usenet. Superior mission-specific features like partial file preview that will download/decode/play the first segment of a MP3 or MPG with just a double-click, Full yEnc support, and Emergency Restart that automatically resumes interrupted downloads without starting over.

http://www.wmhsoft.com/NewsShark/

Agent 2.0 is the top-rated Usenet newsreader on the Internet. Agent is also an excellent POP email client.
This high level of integration between Usenet news and POP email separates Agent from all other communication products. Whether you are downloading yEnc binaries or responding to email, Agent provides you with all the right features.
Agent is also the most mature newsreader on the market. Since the introduction of "Agent .99" in 1994, Agent has always maintained the highest possible ratings from the most trusted sites for Internet software.

http://www.forteinc.com/agent